The Cultural Department is comprised of a seven-member Board of Directors and a full-time staff. The Cultural Department oversees all aspects of cultural education, museum development, use of the Pow Wow Grounds, cultural programs, and related activities and events. The Cultural Department hosts a number of unique events on an annual basis including the Creek Indian Art Show, Sovereignty Celebration, Calvin McGhee Memorial, and the Annual Thanksgiving Pow Wow.

The Cultural Department hosts a variety of special programs including Pow Wow Club, Poarch Creek Princess Program and Competition, Community Stickball Games, Native Youth Issue Forums, and Elder Recognition Program. Traditional Culture and Arts Classes included: Creek Basketry, Finger-weaving, Traditional Clothing, Shell Carving, Creek Language, and Creek Patchwork.